Cardiovascular

The MMI Advantage

Experience and Expertise

MMI’s experts are recognized leaders in cardiovascular, cardiothoracic and peripheral vascular imaging and medicine. Our depth and diversity of experts allows us to provide support for all major diagnostic imaging modalities and treatments in a single core lab.

Modality Expertise

Angiography / Venography

X-Ray

Duplex Ultrasound

CT / CTA / CTV

Cardiac MRI

Echocardiography

MMI provides access to leading experts in peripheral vascular and cardiovascular imaging and medicine. Our team of vascular surgeons, interventional radiologists and cardiologists provide world class expertise on study design, protocol development, and medical image analysis for clinical trials. Our clinical trial experience includes regulated and post-market studies for drug delivery catheters, peripheral vascular stents and atherectomy devices, thrombectomy devices, IVC filters, valve replacement, and more.

We are experienced in all major quantitative and qualitative grading systems to assess disease severity and response to therapy via medical imaging. We offer a variety of validated tools and techniques to facilitate these evaluations, including QVA, QCA, and CT analysis software. Our proprietary data management platform is 21 CFR Part-11 compliant and our patented technology offers unique visualization and data monitoring capabilities.

WHAT WE OFFER

Analysis Capabilities

Quantitative vessel characterization (e.g. diameter, residual percent stenosis)

Quantitative lesion characterization (e.g. lesion length, diameter)

Vessel patency (Doppler ultrasound evaluation)

Vessel revascularization, TIMI flow

Vessel dissection and perforation

Pulmonary embolism (e.g. Modified Miller Index, RV/LV diameter ratio)

Luminal flow obstruction

Device deployment accuracy & integrity (e.g. migration, location, fracture)

Cardiac function (e.g. volumetrics, ejection fraction, cardiac mass)

Regurgitation severity

Valve structural characterization (e.g. calcification, thickening, stenosis)

Valve functional characterization (e.g. velocity ratio, vena contracta width, effective orifice area)

Reduction in vessel stenosis (pre-device) and revascularization (post-device) in peripheral artery disease

Chest CTA taken pre- and post-removal of submissive pulmonary embolism

Pre and post-removal of submissive pulmonary embolism: reconstructed 4-chamber view measuring ventricular diameter

Post-treatment revascularization of the coronary artery

Some of Our Experts

Peter A. Schneider, MD, FACC

Professor of Surgery, Division of Vascular & Endovascular Surgery, University of California – San Francisco; Founding Partner, InRoad Medical

Dr. Schneider is a Distinguished Fellow of the Society for Vascular Surgery and is the past president of Western Vascular Society and Vascular and Interventional Advances (VIVA). He has been invited to numerous national and international visiting professorships, served as director, faculty, or course director for many specialty courses and performed revascularization procedures in more than a dozen countries. He has co-authored multiple books on vascular disease, developed several medical devices, and holds numerous patents. Dr. Schneider was the founding member and chief of the Division of Vascular Surgery at Kaiser Permanente in Hawaii from 1994-2018, where he oversaw the development of the first endovascular operating room in the Kaiser healthcare system. At Kaiser, he developed a Diabetic Limb Treatment Program and a surveillance program for patients with aneurysms and a registry for patients with carotid disease used for surveillance.

David Deaton, MD, FACC

Adjunct Associate Professor of Surgery, University of Pennsylvania Perelman School of Medicine;
Founding Partner, InRoad Medical

Dr. Deaton was deeply involved in the development of endovascular aortic therapy beginning with pre-clinical work in 1993 and significantly contributed to many interventional/endovascular techniques over the last three decades. Dr. Deaton has practiced in a variety of private and academic settings, most recently as Chief – Division of Vascular and Endovascular Surgery at MedStar Georgetown University Hospital in Washington, DC and Thinkas Director, Clinical Vascular Research and Founder and Medical Director, Vascular Non-Invasive Laboratory. Previously, he served as Chief Medical Officer for Endologix and Syntactx, in addition to consulting for a variety of start-up and established medical device companies. Dr. Deaton has held leadership positions in several vascular societies (SVS, PVSS, Chesapeake Vascular), most recently as Chairman of the Political Action Committee of the SVS.

Relevant Scientific Resources

CV Webinar

Clinical Trial Design and Considerations for Below-the-Knee Interventions and Amputation Prevention

MMI’s peripheral vascular experts discuss imaging assessments for evaluating structural and functional changes in vessels.

Medtronic has just announced its first FDA approval for an MRI-friendly internal defibrillator.

CV News

Medtronic receives first FDA approval for MRI friendly defibrillator implant

Medtronic has just announced its first FDA approval for an MRI-friendly internal defibrillator.

Key Publications Involving MMI

Auger DA, Bilchick KC, Gonzalez JA, et al. Imaging left-ventricular mechanical activation in heart failure patients using cine DENSE MRI: Validation and implications for cardiac resynchronization therapy. J Magn Reson Imaging. 2017;46(3):887-896.

Sista AK, Bhatheja R, Rali P, et al. First-in-Human Study to Assess the Safety and Feasibility of the Bashir Endovascular Catheter for the Treatment of Acute Intermediate-Risk Pulmonary Embolism. Circ Cardiovasc Interv. 2021;14(1):e009611.

Zhu YI, Yoon H, Zhao AX, et al. Leveraging the Imaging Transmit Pulse to Manipulate Phase-Change Nanodroplets for Contrast-Enhanced Ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2019;66(4):692-700.

Let MMI provide insights into your clinical study imaging.

Have questions? We’ll connect you immediately to one of our scientific managers and imaging experts. Your time is precious, and we want to make the most out of it.