Arthritis and 

Rheumatic
Diseases

Spine
Spine
Orthopedics
Orthopedics
Cardiovascular
Cardiovascular
Otorhino – laryngology
Otorhino – laryngology
Neurology
Neurology
Thoraco – abdominal
Thoraco – abdominal
Arthritis & Rheumatic Diseases
Group 2096

The MMI Advantage

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Streamlined proprietary
analysis platform

MMI EPICTM customizability allows for efficient analysis of varied assessments across a visually-guided joint mapping user interface.

Experienced with all major joints in the body
Leveraged orthopedic
joint experience

Our 15+ years of experience in orthopedic imaging trials informs a nuanced understanding of soft tissue and joint space changes and disease states.

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Luminary key opinion
leaders

MMI's partnerships with leaders in the rheumatology and orthopedics fields ensures excellence in consulting and analysis needs.

Experience and Expertise

MMI supports the trial imaging needs for a range of inflammatory disease conditions, including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis. 

TA_ENT

Modality Expertise

X-ray
CT
MRI

MMI’s experience in the joint space ranges across the entire human body, including but not limited to those of the hip, knee, ankle, wrist, elbow, and peripheral joints. We support clinical studies for treatments ranging from drugs, immunomodulating biologics, genetic and cellular therapies, as well as emerging technologies.

We support the joint analysis necessary to provide a thorough understanding of the conditional changes encountered in arthritic conditions such as osteoarthritis (OA), rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis, as well as numerous other immune-related states throughout the body systems, such as tendinitis, synovitis and bursitis, and rhinosinusitis.

Determination of disease progression is accomplished through robust tracking of semi-quantitative scoring (such as erosion and joint space narrowing), as well as qualitative changes over time. MMI’s flexible software configuration is fully customizable for a variety of scoring methods and set up with reader accessibility in mind: joint mapping, directed workflow, and straight-forward adjudication.

WHAT WE OFFER

Analysis Capabilities

Sharp scoring (original & modified Genant /
van der Heijde)

Larsen scoring (original & modified Scott)

OMERACT RAMRIS (MRI scoring)

Quantitative Joint Space Narrowing measurements

Simple Erosion Narrowing Score (SENS)

Kellgren-Lawrence grading

Psoriatic Arthritis Ratingen Score (PARS)

Stoke Ankylosing Spondylitis Spine Score

Subluxation

Raw vs. change score reporting

Image Quality Evaluations

3D modeling of the maxillary and ethmoid sinuses
Zinreich scores of right anterior and posterior ethmoid sinuses on sagittal CT
Zinreich scores of right anterior and posterior ethmoid sinuses on sagittal CT
Digital subtraction technique for determining the difference between baseline and post-treatment images to identify areas of reduced sinus opacification
Digital subtraction technique for determining the difference between baseline and post-treatment images to identify areas of reduced sinus opacification
Quantification of ethmoid (yellow) and maxillary (blue) sinus opacification in coronal CT
Quantification of ethmoid (yellow) and maxillary (blue) sinus opacification in coronal CT
Assessment of mucosal thickening in maxillary sinus on axial CT
Zinreich scores of left and right maxillary sinuses on coronal CT
Zinreich scores of left and right maxillary sinuses on coronal CT
3D reconstruction of total ethmoid (yellow) and maxillary (blue) sinus volumes
3D reconstruction of total ethmoid (yellow) and maxillary (blue) sinus volumes
3D reconstruction of total ethmoid (yellow) and maxillary (blue) sinus volumes overlaid on top of partial skull reconstruction
3D reconstruction of total ethmoid (yellow) and maxillary (blue) sinus volumes overlaid on top of partial skull reconstruction

Some of Our Experts

Mark Schweitzer, MD

Vice President of Health Affairs,
Wayne State University

Dr. Schweitzer is fellowship-trained in osteoradiology, and has over 30 years’ experience in research, education, and clinical practice. Dr. Schweitzer is the former presiding officer of the Radiological Society of North America (RSNA) and International Skeletal Society (ISS), is the current Editor-in-Chief of JMRI, and serves on the Editorial Board of MRM. He has published over 400 peer-reviewed papers, 68 book chapters and 4 books, and delivered 800 lectures in 38 countries. Dr. Schweitzer is also an experienced scientific advisory panel member for FDA and NIH.

David Salonen, MD, FRCP

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Bio here

Relevant Scientific Resources

ENTPublication
3D Image Analysis for Staging Chronic Rhinosinusitis
Semi-automated quantitative measurements of sinus inflammation from 3D CT imaging correlate well with clinical outcomes.
Read More

Key Publications Involving MMI

Let MMI provide insights into your clinical study imaging.

Have questions? We’ll connect you immediately to one of our scientific managers and imaging experts. Your time is precious, and we want to make the most out of it.

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